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Product Name FUT5 Chinese Name FUT5抗体 Alias UT5_HUMAN; Alpha-(1,3)-fucosyltransferase; Fucosyltransferase 5; Fucosyltransferase V; Fuc-TV; FucT-V; Galactoside 3-L-fucosyltransferase. Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 41kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FUT5: 281-374/374 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]
Function:
May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.
Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity:
Liver, colon and testis and trace amounts in T-cells and brain.
Similarity:
Belongs to the glycosyltransferase 10 family.
SWISS:
Q11128
Gene ID:
2527
Database links:Entrez Gene: 10690 Human
Entrez Gene: 2526 Human
Entrez Gene: 2527 Human
Entrez Gene: 2528 Human
Entrez Gene: 2529 Human
Omim: 136835 Human
SwissProt: P22083 Human
SwissProt: P51993 Human
SwissProt: Q11128 Human
SwissProt: Q11130 Human
SwissProt: Q9Y231 Human
Unigene: 390420 Human
Unigene: 457 Human
Unigene: 49117 Human
Unigene: 572064 Human
Unigene: 623098 Human
Unigene: 631843 Human
Unigene: 631846 Human
Unigene: 705615 Human
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