Product Name	IL-19
Chinese Name	白细胞介素19抗体
Alias	Interleukin-19; IL 10C; IL 19; Interleukin 19; MDA1;ZMDA1; IL-19; Melanoma differentiation-associated protein-like protein; NG.1; IL19_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
Applications	WB=1:500-1000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	20kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IL-19/NG.1: 81-177/177
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq]. Function: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Subcellular Location: Secreted. Similarity: Belongs to the IL-10 family. SWISS: Q9UHD0 Gene ID: 29949 Database links: Entrez Gene: 29949 Human Entrez Gene: 329244 Mouse Omim: 605687 Human SwissProt: Q9UHD0 Human SwissProt: Q8CJ70 Mouse Unigene: 661017 Human Unigene: 131480 Mouse
Product Picture	Sample: Jurkat cell(human) Lysate at 30 ug Primary: Anti- IL-19(SL10087R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20kD Observed band size: 20 kD Sample: Lane 1: Mouse Spleen Lysates Lane 2: Mouse Skin Lysates Lane 3: Mouse Uterus Lysates Primary: Anti-IL-19 (SL10087R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kDa Observed band size: 27 kDa

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