Product Name	GM-CSF
Chinese Name	粒细胞-巨噬细胞克隆刺激因子抗体
Alias	Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN; CSF2_MOUSE.
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Pig,  (predicted: Mouse, Rat, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse GM-CSF: 71-141/141
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]. Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Subunit: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits. Subcellular Location: Secreted. Similarity: Belongs to the GM-CSF family. SWISS: P01587 Gene ID: 12981 Database links: Entrez Gene: 12981 Mouse SwissProt: P01587 Mouse Unigene: 4922 Mouse GM-CSF是vascular endothelial cell、单核细胞和成纤维细胞合成的glycoprotein。能促进中性粒细胞成熟；刺激成熟的粒细胞从骨髓释出；增强中性粒细胞趋化及吞噬功能。
Product Picture	Sample: Lane 1: Recombined Trx/His-tag porcine GM-CSF protein (Aa18-144) at 5 ug Lane 2: Recombined His-tag porcine GM-CSF protein Primary: Anti-GM-CSF (SL0999R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 33/15 kD Observed band size: 33/15 kD

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