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Rabbit Anti-Human Serum albumin (Loading Control)antibody
Rabbit Anti-Human Serum albumin (Loading Control)antibody
ALB; ALBU_HUMAN; Albumin (32 AA); Albumin (AA 34); Analbuminemia; Bisalbuminemia; Cell growth inhibiting protein 42; DKFZp779N1935; Dysalbuminemic hyperthyroxinemia; Growth inhibiting protein 20; HSA; Hyperthyroxinemia dysalbuminemic; PRO0883; PRO0903; PR
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  • NO.:SL0945R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,Rat,Goat,(predicted: Dog,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Product Name Human Serum albumin (Loading Control)
Chinese Name 白蛋白(内参)抗体
Alias ALB; ALBU_HUMAN; Albumin (32 AA); Albumin (AA 34); Analbuminemia; Bisalbuminemia; Cell growth inhibiting protein 42; DKFZp779N1935; Dysalbuminemic hyperthyroxinemia; Growth inhibiting protein 20; HSA; Hyperthyroxinemia dysalbuminemic; PRO0883; PRO0903; PRO1341; PRO2044; PRO2619; Serum albumin.   人血清白蛋白
literatures
Specific References  (4)     |     SL0945R has been referenced in 4 publications.
[IF=4.04] Xia, Tingting, et al. "A novel magnetic/photoluminescence bifunctional nanohybrid for the determination of trypsin." Talanta (2017).  other ;  
[IF=3.998] Jik-Han Jung. et al. Dual size-exclusion chromatography for efficient isolation of extracellular vesicles from bone marrow derived human plasma. Sci Rep-Uk. 2021; 11: 217  WB ;  Human.  
[IF=2.775] Sheng Deng. et al. Xuefu Zhuyu decoction improves asthma-induced asthenozoospermia based on network pharmacology and in vivo experiment. 2021 Aug 10  WB,IHC ;  Rat.  
[IF=1.918] Wang J et al. Effect of Asthma on Erectile Dysfunction in Rats as Determined by Biological Network AnalysisMed Sci Monit.2020 Dec 20;26:e927491.  WB ;  Rat.  
Product Type Internal reference anti 
Research Area Tumour  Cell biology  immunology  Developmental biology  Stem cells  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse, Rat, Goat,  (predicted: Dog, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 69kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen human Serum albumin puritied 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].

Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Post-translational modifications:
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

DISEASE:
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Similarity:
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.

SWISS:
P02769

Gene ID:
280717

Database links:

Entrez Gene: 213 Human

Omim: 103600 Human

SwissProt: P02768 Human

Unigene: 418167 Human



Product Picture
Sample:
Lane 1: Mouse Serum
Lane 2: Rat Serum
Lane 3: Human Serum
Lane 4: Goat Serum
Primary: Anti-Human Serum albumin (SL0945R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kDa
Observed band size: 62 kDa
Sample:
Lane 1: Serum (Human) at 20 ug
Lane 2: Serum (Mouse) at 20 ug
Lane 3: Serum (Rat) at 20 ug
Lane 4: Serum (Goat) at 20 ug
Lane 5: Liver (Rat) tissue lysates at 40 ug
Primary: Anti-Human Serum albumin (SL0945R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kD
Observed band size: 65 kD
Sample:HepG2 Cell (Human) Lysate at 40 ug
Primary: Anti-Serum albumin (SL0945R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kD
Observed band size: 69 kD

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