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Product Name Batroxobin Chinese Name 蝮蛇蛇毒巴曲酶/类凝血酶抗体 Alias Agkistrodon halys Batroxobin; Thrombin-like enzyme batroxobin; BX; SVTLE; Bothrops atrox serine proteinase; Defibrase; Fibrinogen-clotting enzyme; Reptilase; Snake venom serine protease; SVSP; Venombin A. 蝮蛇巴曲霉毒素; 蝮蛇蛇毒巴曲酶毒素; Research Area immunology Immunogen Species Rabbit Clonality Polyclonal Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 25kDa Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from Bothrops atrox Batroxobin: 165-231/255 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail No data available.
Function:
Thrombin-like snake venom serine protease. Cleaves Arg-Gly bonds in fibrinogen alpha chains (FGA).
Subunit:
Secreted.
Subcellular Location:
Expressed by the venom gland.
Similarity:
Belongs to the peptidase S1 family. Snake venom subfamily.
Contains 1 peptidase S1 domain.
SWISS:
P04971
Gene ID:
N/A
Batroxobin蛇毒巴曲酶蛋白是经生物工程提纯、精制而得丝氨酸蛋白酶。
其作用机制为:
①具有分解血纤维蛋白原、抑制血栓形成作用。 ②具有诱发TPA的释放、增强TPA的作用、促进纤维蛋白溶酶的生成、减少α2-P1和PAI、溶解血栓的作用。
③具有降低血粘度、抑制红细胞凝集、沉降、增强红细胞的血管通过性及变形能力、降低血管阻力以及改善微循环等作用。使溶栓作用快速,缺血部位功能恢复,从而达到治疗和防止复发的效果。
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