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Rabbit Anti-Batroxobin antibody
Rabbit Anti-Batroxobin antibody
Agkistrodon halys Batroxobin; Thrombin-like enzyme batroxobin; BX; SVTLE; Bothrops atrox serine proteinase; Defibrase; Fibrinogen-clotting enzyme; Reptilase; Snake venom serine protease; SVSP; Venombin A.蝮蛇巴曲霉毒素; 蝮蛇蛇毒巴曲酶毒素;
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  • NO.:SL0912R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name Batroxobin
Chinese Name 蝮蛇蛇毒巴曲酶/类凝血酶抗体
Alias Agkistrodon halys Batroxobin; Thrombin-like enzyme batroxobin; BX; SVTLE; Bothrops atrox serine proteinase; Defibrase; Fibrinogen-clotting enzyme; Reptilase; Snake venom serine protease; SVSP; Venombin A.  蝮蛇巴曲霉毒素; 蝮蛇蛇毒巴曲酶毒素;
Research Area immunology  
Immunogen Species Rabbit
Clonality Polyclonal
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 25kDa
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from Bothrops atrox Batroxobin: 165-231/255 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail No data available.

Function:
Thrombin-like snake venom serine protease. Cleaves Arg-Gly bonds in fibrinogen alpha chains (FGA).

Subunit:
Secreted.

Subcellular Location:
Expressed by the venom gland.

Similarity:
Belongs to the peptidase S1 family. Snake venom subfamily.
Contains 1 peptidase S1 domain.

SWISS:
P04971

Gene ID:
N/A

Batroxobin蛇毒巴曲酶蛋白是经生物工程提纯、精制而得丝氨酸蛋白酶。
其作用机制为:

①具有分解血纤维蛋白原、抑制血栓形成作用。 ②具有诱发TPA的释放、增强TPA的作用、促进纤维蛋白溶酶的生成、减少α2-P1和PAI、溶解血栓的作用。
③具有降低血粘度、抑制红细胞凝集、沉降、增强红细胞的血管通过性及变形能力、降低血管阻力以及改善微循环等作用。使溶栓作用快速,缺血部位功能恢复,从而达到治疗和防止复发的效果。

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