Product Name	intestinal FABP
Chinese Name	小肠型脂肪酸Binding protein抗体
Alias	FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; I FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; OTTHUMP00000163925.
Research Area	immunology  Growth factors and hormones  Kinases and Phosphatases  Diabetes
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	28kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IFABP: 31-132/132
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). [Subcellular Location] Cytoplasm (By similarity). [Similarity] Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. SWISS: P12104 Gene ID: 2169 Database links: Entrez Gene: 2169 Human Entrez Gene: 14079 Mouse Entrez Gene: 25598 Rat Omim: 134640 Human SwissProt: P12104 Human SwissProt: P55050 Mouse SwissProt: Q53YP5 Mouse SwissProt: P02693 Rat Unigene: 282265 Human Unigene: 28398 Mouse Unigene: 91358 Rat 小肠脂肪酸Binding protein(IFABP)主要是在小肠分泌的一种蛋白质,参与了脂肪酸的吸收和代谢。IFABP有可能通过干扰脂肪酸代谢而影响胰岛素敏感性。 IFABP主要用于2型Diabetes相关性的研究。

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