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Rabbit Anti-HHV4/CMV antibody
Rabbit Anti-HHV4/CMV antibody
EB2_EBVB9; mRNA export factor EB2; Mta; ORF57 protein homolog; Protein SM; BSLF2; BMLF1; ORF57; HHV4tp2_gp21HHV4; EBV; Human herpesvirus 4 type 2.
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  • NO.:SL0866R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Product Name HHV4/CMV
Chinese Name 人类巨细胞病毒抗体
Alias EB2_EBVB9; mRNA export factor EB2; Mta; ORF57 protein homolog; Protein SM; BSLF2; BMLF1; ORF57; HHV4tp2_gp21HHV4; EBV; Human herpesvirus 4 type 2.  
Research Area immunology  Bacteria and viruses  
Immunogen Species Rabbit
Clonality Polyclonal
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 53kDa
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from HHV4 2: 201-300/479 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail ORF57 herpesvirus core gene UL54 family.
No data available.

Function:
Promotes the nuclear export of a subset of early and late viral mRNAs by interacting with mRNAs and cellular export proteins. Additionally may prevent the establishment of cellular antiviral state, by acting as an alternative splicing factor for cellular RNAs such as STAT1, resulting in a STAT1 mRNA incapable of producing the STAT1alpha isoform.

Subunit:
Interacts with host XPO1 and with the XPO1 export pathway components small GTPase RAN and nucleoporin NUP214. Interacts with host SPEN, OTT1 and OTT3.

Subcellular Location:
Host nucleus. Host cytoplasm. Note=shuttles between the nucleus and the cytoplasm.

Post-translational modifications:
Phosphorylated by cellular protein kinase CK2.

Similarity:
Belongs to the HHV-1 ICP27 protein family.

SWISS:
Q04360

Gene ID:
N/A

Database links:

SwissProt: Q04360 Epstein-Barr virus



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