Product Name	Resistin
Chinese Name	抵抗素抗体
Alias	Adipose tissue specific secretory factor; ADSF; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein; C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 1; Cysteine rich secreted protein A12 alpha like 2; Cysteine rich secreted protein FIZZ3; FIZZ 3; FIZZ3; Found in inflammatory zone 3; HXCP 1; HXCP1; MGC126603; MGC126609; PRO1199; Resistin delta2; RETN 1; RETN; RETN1; RSTN; UNQ407; XCP 1; XCP1
literatures	Specific References  (1)     |     SL0795R has been referenced in 1 publications. [IF=7.419] Hirona Kugo. et al. Tricaprin can prevent the development of AAA by attenuating aortic degeneration. BIOMED PHARMACOTHER. 2023 Apr;160:114299  IHC ;  Rat.   PubMed:36724640
Research Area	Cardiovascular  Cell biology  immunology  Neurobiology  Signal transduction  Growth factors and hormones  Kinases and Phosphatases  Diabetes  Endocrinopathy
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Mouse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Resistin: 21-114/114
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. [provided by RefSeq] Function: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Subcellular Location: Secreted. Tissue Specificity: Expressed only in fatty tissues. Similarity: Belongs to the resistin/FIZZ family. SWISS: Q9HD89 Gene ID: 56729 Database links: Entrez Gene: 56729 Human Entrez Gene: 57264 Mouse Omim: 605565 Human SwissProt: Q9HD89 Human SwissProt: Q99P87 Mouse Unigene: 283091 Human Unigene: 1181 Mouse 抵抗素Resistin, 是一种肽激素，富含半胱氨酸的分泌蛋白， 由脂肪细胞分泌的多肽类激素,属于RELM家族，也称之为ADSF（脂肪组织特异性的分泌因子）,抵抗素可能是肥胖和胰岛素抵抗之间的重要链接。近期研究结果显示,抵抗素 (Resistin)还是一种重要的脂肪组织旁分泌调质, 参与内vascular endothelial cell功能稳态的调节, 在二型DiabetesCardiovascular病变发生发展过程中发挥重要病理生理学作用.
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat breast); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Resistin) Polyclonal Antibody, Unconjugated (SL0795R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Tissue/cell: rat liver tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Resistin Polyclonal Antibody, Unconjugated(SL0795R) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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