Product Name	C10orf46
Chinese Name	CULLIN抗体
Alias	C10orf46; chromosome 10 open reading frame 46; Cullin; FLJ40409; MGC33215; OTTHUMP00000046870; Uncharacterized protein C10orf46 homolog; CACL1_HUMAN; CDK2-associated and cullin domain-containing protein 1; Cdk-associated cullin1; CACUL1; CAC1.
Research Area	Tumour
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34/41kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from the middle of human CACUL1: 181-248/306
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	C10orf46 belongs to the cullin family. There are 3 isoforms. Function: Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. Subunit: Interacts with CDK2. Tissue Specificity: Ubiquitously expressed with highest expression in the mammary gland and large intestine. Highly expressed in cancer tissues and cancer cell lines. During cell cycle progression expression is high in G1/S, low in the middle of S phase, and increases again in S/G2 phase. Similarity: Belongs to the cullin family. SWISS: Q86Y37 Gene ID: 143384 Database links: Entrez Gene: 143384 Human SwissProt: Q86Y37 Human SwissProt: Q8R0X2 Mouse CULLIN 在细胞周期中起重要作用，主要用于各种Tumour的研究.

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