Product Name	Chromogranin B
Chinese Name	嗜铬粒素B抗体
Alias	Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.
Research Area	Tumour  Neurobiology  Endocrinopathy
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	72kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse CGB: 601-677/677
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009]. Function: Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. Subcellular Location: Secreted. Note=Neuroendocrine and endocrine secretory granules. Tissue Specificity: Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. Post-translational modifications: Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. O-glycosylated. Similarity: Belongs to the chromogranin/secretogranin protein family. SWISS: P16014 Gene ID: 12653 Database links: Entrez Gene: 1114 Human Entrez Gene: 12653 Mouse Entrez Gene: 24259 Rat Omim: 118920 Human SwissProt: P05060 Human SwissProt: P16014 Mouse SwissProt: O35314 Rat Unigene: 516874 Human Unigene: 11090 Rat 嗜铬粒素B在肾上腺 垂体 胸腺 子宫 卵巢等神经内分泌组织表达该蛋白成分较多。

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