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Product Name Anti-RAP2C/RBITC Chinese Name 罗丹明(RBITC)标记的RAP2C蛋白抗体 Alias 2010200P20Rik; AI194294; AL022976; BOS_25229; DKFZp313B211; MGC143331; OTTHUMP00000024037; OTTMUSP00000019067; RAP2C; RAP2C, member of RAS oncogene family; RAP2C_HUMAN; Ras related protein Rap 2c; Ras-related protein Rap-2c; RP23-15D12.2. Research Area Cell biology Signal transduction G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 21kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RAP2C Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
Subcellular Location:
Cytoplasm. Recycling endosome membrane.
Post-translational modifications:
Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
DISEASE:
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
Similarity:
Belongs to the small GTPase superfamily. Ras family.
Database links:
Entrez Gene: 57826 Human
Entrez Gene: 72065 Mouse
Entrez Gene: 474323 Zebrafish
SwissProt: Q9Y3L5 Human
SwissProt: Q8BU31 Mouse
Unigene: 119889 Human
Unigene: 743556 Human
Unigene: 43152 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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