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Rabbit Anti-RAP2C/RBITC Conjugated antibody
Rabbit Anti-RAP2C/RBITC Conjugated antibody
2010200P20Rik; AI194294; AL022976; BOS_25229; DKFZp313B211; MGC143331; OTTHUMP00000024037; OTTMUSP00000019067; RAP2C; RAP2C, member of RAS oncogene family; RAP2C_HUMAN; Ras related protein Rap 2c; Ras-related protein Rap-2c; RP23-15D12.2.
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  • NO.:SL21156R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-RAP2C/RBITC
Chinese Name 罗丹明(RBITC)标记的RAP2C蛋白抗体
Alias 2010200P20Rik; AI194294; AL022976; BOS_25229; DKFZp313B211; MGC143331; OTTHUMP00000024037; OTTMUSP00000019067; RAP2C; RAP2C, member of RAS oncogene family; RAP2C_HUMAN; Ras related protein Rap 2c; Ras-related protein Rap-2c; RP23-15D12.2.  
Research Area Cell biology  Signal transduction  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 21kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RAP2C
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.

Subcellular Location:
Cytoplasm. Recycling endosome membrane.

Post-translational modifications:
Palmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.

DISEASE:
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

Database links:

Entrez Gene: 515181 Cow

Entrez Gene: 57826 Human

Entrez Gene: 72065 Mouse

Entrez Gene: 474323 Zebrafish

SwissProt: Q08DI5 Cow

SwissProt: Q9Y3L5 Human

SwissProt: Q8BU31 Mouse

Unigene: 119889 Human

Unigene: 743556 Human

Unigene: 43152 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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