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Rabbit Anti-MCP3/RBITC Conjugated antibody
Rabbit Anti-MCP3/RBITC Conjugated antibody
C-C motif chemokine 7; CCL7; CCL7_HUMAN; Chemokine CC Motif Ligand 7; FIC; MARC; MCP-3; MCP3; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; NC28; RP23-350G1.4; SCYA6; SCYA7; Small inducible cytokine A7; Small-inducible cytokine A7.
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  • NO.:SL1987R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Mouse,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-MCP3/RBITC
Chinese Name 罗丹明(RBITC)标记的单核细胞趋化蛋白3抗体
Alias C-C motif chemokine 7; CCL7; CCL7_HUMAN; Chemokine CC Motif Ligand 7; FIC; MARC; MCP-3; MCP3; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; NC28; RP23-350G1.4; SCYA6; SCYA7; Small inducible cytokine A7; Small-inducible cytokine A7.  
Research Area Tumour  immunology  Growth factors and hormones  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Mouse, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 11kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from mouse MCP-3
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]

Function:
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Post-translational modifications:
O-glycosylated.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

Database links:

Entrez Gene: 20306 Mouse

SwissProt: Q03366 Mouse

Unigene: 341574 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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