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Product Name Anti-CKS1/RBITC Chinese Name 罗丹明(RBITC)标记的Cyclin依赖性激酶调节亚基1抗体 Alias CDC2 associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; Cell division control protein CKS1; CKS 1; CKS1B; Ckshs1; Cyclin dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS 143; PNAS 16; PNAS 18. Research Area Tumour Cell biology immunology Cyclin Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 9.6kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CKS1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
Function:
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Subunit:
Forms a homohexamer that can probably bind six kinase subunits.
Similarity:
Belongs to the CKS family.
Database links:Entrez Gene: 1163 Human
Entrez Gene: 54124 Mouse
Omim: 116900 Human
SwissProt: P61024 Human
SwissProt: P61025 Mouse
Unigene: 374378 Human
Unigene: 3049 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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