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Rabbit Anti-GSH2/PE-Cy7 Conjugated antibody
Rabbit Anti-GSH2/PE-Cy7 Conjugated antibody
GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2.
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Details

Product Name Anti-GSH2/PE-Cy7
Chinese Name PE-Cy7标记的GSH2蛋白抗体
Alias GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2.  
Research Area Cell biology  Transporter  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 32kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GSH2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure. The homeobox DNA-binding domain is commonly found in proteins that play a role in development and are involved in transcriptional regulation and the control of gene expression. GSH-2 (GS homeobox-2), also known as GSX2, is a 304 amino acid protein that contains one homeobox DNA-binding domain. Localized to the nucleus, GSH-2 is thought to function as a transcription factor that selectively binds the DNA sequence 5'-CNAATTAG-3'. Specifically, GSH-2 may be involved in neuronal differentiation, playing a role in spinal cord development.

Function:
Probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3' (By similarity).

Subcellular Location:
Nucleus (By similarity).

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 170825 Human

Entrez Gene: 14843 Mouse

Entrez Gene: 364140 Rat

SwissProt: Q9BZM3 Human

SwissProt: P31316 Mouse

Unigene: 371899 Human

Unigene: 218752 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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