Product Name	Anti-MrpL39/PE-Cy5.5
Chinese Name	PE-Cy5.5标记的Mitochondrion核糖体蛋白L39
Alias	L39mt; Mitochondrial ribosomal protein L39; MRP L5; MRPL5; MSTP003; PRED22; PRED66; RPML5; RM39_HUMAN.
Research Area	Tumour  immunology  Chromatin and nuclear signals  Signal transduction  transcriptional regulatory factor  Mitochondrion  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	39kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MrpL-39
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. Subcellular Location: Mitochondrion. Tissue Specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is heart-specific. Similarity: To the N-terminal of threonyl-tRNA synthetases. Database links: Entrez Gene: 54148 Human Entrez Gene: 27393 Mouse Omim: 611845 Human SwissProt: Q9NYK5 Human SwissProt: Q9JKF7 Mouse Unigene: 420696 Human Unigene: 103655 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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