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Rabbit Anti-MRGPRA/HRP Conjugated antibody
Rabbit Anti-MRGPRA/HRP Conjugated antibody
Adenine receptor; G protein coupled receptor rc 56 1 3; Mas related G protein coupled receptor member A; Mas related gene A; MGC108580; Mrg A; Mrga 10; MrgA; Mrgpra; Nuclear receptor MrgA10 RF amide G protein coupled receptor.
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  • NO.:SL17756R-HRP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Rat,)
    Applications:WB ELISA IHC-P IHC-F ICC
    concentration:1mg/ml
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Product Name Anti-MRGPRA/HRP
Chinese Name 辣根过氧化物酶标记的腺嘌呤受体抗体
Alias Adenine receptor; G protein coupled receptor rc 56 1 3; Mas related G protein coupled receptor member A; Mas related gene A; MGC108580; Mrg A; Mrga 10; MrgA; Mrgpra; Nuclear receptor MrgA10 RF amide G protein coupled receptor.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Rat, )
Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from rat MRGPRA
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
MRGPRA, Mas-related G-protein coupled receptor member A, is an orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. It mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins and it may regulate the function of nociceptive neurons by modulation of pain perception.

Function:
] Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity).

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.

Similarity:
Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.

Database links:

Entrez Gene: 252960 Rat

SwissProt: Q7TN49 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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