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Product Name Anti-SPATA5/HRP Chinese Name 辣根过氧化物酶标记的精子发生相关蛋白2抗体 Alias AFG2; ATPase family gene 2 homolog; ATPase family protein 2 homolog; SPAF; Spermatogenesis associated 5; Spermatogenesis associated factor SPAF; Spermatogenesis-associated factor protein. Research Area Cell biology Developmental biology Stem cells Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) Applications WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 98kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SPATA5 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SPATA5 is an 893 amino acid protein that localizes to cytoplasm and mitochondrion, and may be involved in morphological and functional mitochondrial transformations during spermatogenesis. Existing as three alternatively spliced isoforms, SPATA5 belongs to the AAA ATPase family and the AFG2 subfamily. The gene that encodes SPATA5 consists of more than 396,000 bases and maps to human chromosome 4q28.1. Housing nearly 900 genes, chromosome 4 represents approximately 6% of the human genome and is associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Function:
May be involved in morphological and functional mitochondrial transformations during spermatogenesis.
Subcellular Location:
Cytoplasmic and Mitochondrial
Similarity:
Belongs to the AAA ATPase family. AFG2 subfamily.
Database links:Entrez Gene: 166378 Human
Entrez Gene: 57815 Mouse
SwissProt: Q8NB90 Human
SwissProt: Q3UMC0 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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