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Rabbit Anti-SCARF2/Cy7 Conjugated antibody
Rabbit Anti-SCARF2/Cy7 Conjugated antibody
NSR1; Scarf2; Scavenger receptor class F member 2; Scavenger receptor expressed by endothelial cells 2 protein; SREC-II; SREC2; SREC2_HUMAN; SRECRP-1; SREPCR.
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Details

Product Name Anti-SCARF2/Cy7
Chinese Name Cy7标记的清道夫受体F2抗体
Alias NSR1; Scarf2; Scavenger receptor class F member 2; Scavenger receptor expressed by endothelial cells 2 protein; SREC-II; SREC2; SREC2_HUMAN; SRECRP-1; SREPCR.  
Research Area Cell biology  immunology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 88kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SCARF2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).

Subcellular Location:
Membrane.

Tissue Specificity:
Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.

Similarity:
Contains 7 EGF-like domains.

Database links:

Entrez Gene: 91179 Human

Entrez Gene: 224024 Mouse

Omim: 613619 Human

SwissProt: Q96GP6 Human

SwissProt: P59222 Mouse

Unigene: 474251 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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