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Product Name Anti-MMP27/Cy5.5 Chinese Name Cy5.5标记的基质金属蛋白酶27抗体 Alias EC 3.4.24.; Matrix metallopeptidase 27; Matrix metalloprotease 27; Matrix metalloproteinase 27; Matrix metalloproteinase-27; MMP 27; MMP-27; MMP27; MMP27_HUMAN. Research Area Tumour Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 48kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MMP27 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]
Function:
Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.
Tissue Specificity:
Expressed in B-cells.
Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin repeats.
Database links:Entrez Gene: 64066 Human
Entrez Gene: 234911 Mouse
SwissProt: Q9H306 Human
Unigene: 534479 Human
Unigene: 334940 Mouse
Unigene: 218678 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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