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Product Name Anti-CYPIVF11/Cy5.5 Chinese Name Cy5.5标记的细胞色素P450 IVF11抗体 Alias Cytochrome P450 4F11; CP4FB_HUMAN; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 60kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CYPIVF11 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
CYPIVF11 is a member of the cytochrome P450 family of cytochrome monooxidases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
Subcellular Location:
Endoplasmic reticulum membrane; Single pass membrane protein
Similarity:
Belongs to the cytochrome P450 family.
Database links:Entrez Gene: 57834 Human
Omim: 611517 Human
SwissProt: Q9HBI6 Human
Unigene: 187393 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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