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Product Name Anti-CTRP7/Cy5.5 Chinese Name Cy5.5标记的补体C1qTumour坏死因子相关蛋白7抗体 Alias C1q and tumor necrosis factor related protein 7; C1QT7_HUMAN; C1QTNF7; Complement C1q tumor necrosis factor related protein 7; Complement C1q tumor necrosis factor-related protein 7; CTRP 7; ZACRP7. Research Area Tumour Cell biology immunology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 29kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CTRP7 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
CTRP7 is a 289 amino acid secreted glycoprotein that contains one collagen-like domain and one C1q domain. In young obese mice, transcripts of CTRP1, CTRP2, CTRP3, CTRP6 and CTRP7 are found to be upregulated. CTRP7 is predominantly expressed in adipose tissue and may be a paralog of Acrp30 (adiponectin). Caloric restriction in young animals leads to an increase in serum Acrp30, however this is not the case with older animals. During caloric restriction in older animals, transcription of CTRP2 and CTRP7 is significantly induced in senescent skeletal muscle and myocardium. This however is not sufficient to activate AMPK to the same extent as in younger animals, therefore suggesting that CTRP2 and CTRP7 are not suitable substitutions for Acrp30 function.
Subcellular Location:
Secreted.
Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.
Database links:Entrez Gene: 114905 Human
Entrez Gene: 109323 Mouse
SwissProt: Q9BXJ2 Human
SwissProt: Q8BVD7 Mouse
Unigene: 153714 Human
Unigene: 275553 Mouse
Unigene: 35545 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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