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Product Name Anti-COQ7/Cy5.5 Chinese Name Cy5.5标记的辅酶合成加氧酶COQ7抗体 Alias CAT5; CLK1; Coenzyme Q biosynthesis protein 7 homolog; Coenzyme Q7 homolog ubiquinone; coq7; COQ7 coenzyme Q 7 homolog ubiquinone; COQ7 protein; COQ7_HUMAN; Timing protein clk-1 homolog; Ubiquinone biosynthesis protein COQ7 homolog. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 24kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human COQ7 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Function:
Involved in lifespan determination in ubiquinone-independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator.
Subcellular Location:
Mitochondrion inner membrane. Synthesized as a preprotein that is imported into the mitochondrial matrix, where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane.
Tissue Specificity:
Expressed dominantly in heart and skeletal muscle.
Similarity:
Belongs to the COQ7 family.
Database links:Entrez Gene: 10229 Human
Omim: 601683 Human
SwissProt: Q99807 Human
SwissProt: Q9BTT7 Human
Unigene: 157113 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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