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Product Name Anti-MRP63/Cy5.5 Chinese Name Cy5.5标记的Mitochondrion核糖体蛋白MRP63抗体 Alias bMRP63; hMRP63; MGC3243; mitochondrial; mitochondrial ribosomal protein bMRP63; MRP63; Ribosomal protein 63; Ribosomal protein 63, mitochondrial; RT63_HUMAN. Research Area Cell biology Mitochondrion Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 12kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MRP63 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Mammalian mitochondrial ribosomes (mitoribosomes) are responsible for protein synthesis within the mitochondrion. The mitoribosomes are composed of a 4:1 ratio of protein to RNA, with the proteins forming two subunits, the 28S subunit and the 39S subunit. Across species, the proteins that make up the mitoribosome subunits vary greatly in sequence, preventing easy recognition by sequence homology. MRP-63 102 amino acid protein that has been identified on the intact 55S mitoribosome subunit. It is theorized that MRP-63 localizes to the subunit interface and dissociates from the 55S mitoribosome during subunit separation.
Subcellular Location:
Mitochondrion.
Database links:Entrez Gene: 78988 Human
Omim: 611997 Human
SwissProt: Q9BQC6 Human
Unigene: 458367 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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