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Product Name Anti-GPR52/Cy5.5 Chinese Name Cy5.5标记的G protein-coupled receptor52抗体 Alias GPCR GPR52; axor10; G protein coupled receptor 52; GPR52; GPR52_HUMAN; Probable G protein coupled receptor 52; Probable G-protein coupled receptor 52; GPCR 52. Research Area Cell biology Neurobiology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 41kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GPR52 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR52 (G protein-coupled receptor 52) is a 361 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family and has been found to be expressed in the caudate and putamen regions of the brain. The gene encoding GPR52 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
Function:
Orphan receptor.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 9293 Human
Omim: 604106 Human
SwissProt: Q9Y2T5 Human
Unigene: 673850 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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