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Product Name Anti-C3ORF31 /Cy5.5 Chinese Name Cy5.5标记的3号染色体开放阅读框31抗体 Alias C3orf31; Chromosome 3 open reading frame 31; MGC16471; MMP37 like protein; MMP37 like protein mitochondrial; MMP37-like protein, mitochondrial; MMP37_HUMAN. Research Area Tumour Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 33kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C3ORF31 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
C3orf31 (chromosome 3 open reading frame 31), also known as MGC16471 or DKFZp434E0519, is a 316 amino acid mitochondrial protein that belongs to the MMP37 family and may be involved in translocation of transit peptide-containing proteins across the mitochondrial inner membrane. C3orf24 is encoded by a gene that maps to human chromosome 3p25.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
May be involved in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity).
Subcellular Location:
Mitochondrion (By similarity).
Similarity:
Belongs to the MMP37/TAM41 family.
Database links:
UniProtKB/Swiss-Prot: Q96BW9.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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