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Product Name Anti-Thymosin Alpha-1/Cy5.5 Chinese Name Cy5.5标记的胸腺肽α1抗体 Alias Prothymosin alpha (gene sequence 28); Prothymosin alpha; Prothymosin alpha like 1 protein; Thymalfasin; Thymosin alpha 1 acetate; Thymosin alpha 1; Thymosin alpha; TMSA; PTMA; PTMA_HUMAN. Research Area Tumour immunology Endocrinopathy Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Cow, ) Applications Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 12kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Thymosin Alpha-1(2-29/112) Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin alpha. A peptide containing 28 amino acid residues, named thymosin alpha 1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and in vivo test systems. Thymosin alpha 1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin alpha 1.
Function:
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Subcellular Location:
Nucleus.
Post-translational modifications:
Covalently linked to a small RNA of about 20 nucleotides.
Similarity:
Belongs to the pro/parathymosin family.
Database links:Entrez Gene: 5757 Human
Omim: 188390 Human
SwissProt: P06454 Human
Unigene: 459927 Human
Unigene: 708083 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胸腺素α-1;胸腺肽
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