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Rabbit Anti-Synaptotagmin-4/Cy5.5 Conjugated antibody
Rabbit Anti-Synaptotagmin-4/Cy5.5 Conjugated antibody
SYT4_HUMAN; Syt4; SytIV; HsT1192; KIAA1342; Synaptotagmin IV; SYT4; SYT 4; Syt IV; SytIV; Synaptotagmin4; SynaptotagminIV.
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  • NO.:SL1897R-Cy5.5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-Synaptotagmin-4/Cy5.5
Chinese Name Cy5.5标记的突触Binding protein4抗体
Alias SYT4_HUMAN; Syt4; SytIV; HsT1192; KIAA1342; Synaptotagmin IV; SYT4; SYT 4; Syt IV; SytIV; Synaptotagmin4; SynaptotagminIV.  
Research Area Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 48kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Synaptotagmin-4
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene belongs to the synaptotagmin family. Members of this family are multi-domained, integral membrane proteins of synaptic vesicles, and are thought to serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. This gene is primarily expressed in the nervous tissues. [provided by RefSeq].

Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.

Tissue Specificity:
Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.

Similarity:
Belongs to the synaptotagmin family.
Contains 2 C2 domains.

Database links:

Entrez Gene: 6860 Human

Omim: 600103 Human

SwissProt: Q9H2B2 Human

Unigene: 8059 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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