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Product Name Anti-TIG2/Cy5.5 Chinese Name Cy5.5标记的视黄酸受体应答蛋白2抗体 Alias Rarres2; TIG2; tazarotene induced gene 2; Retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; RAR-responsive protein TIG2; RARR2_HUMAN. Research Area Tumour Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Rat, Rabbit, Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 18kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from rat Rarres2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein. [provided by RefSeq, Dec 2008].
Subcellular Location:
Secreted (Potential).
Tissue Specificity:
Highly expressed in skin (basal and suprabasal layers of the epidermis, hair follicles and endothelial cells). Also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon.
Database links:Entrez Gene: 5919 Human
Entrez Gene: 71660 Mouse
Omim: 601973 Human
SwissProt: Q99969 Human
SwissProt: Q9DD06 Mouse
Unigene: 647064 Human
Unigene: 28231 Mouse
Unigene: 28532 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
视黄酸受体反应蛋白,目前多用于银屑病以及部分Tumour作用机理方面的研究,属于甲状腺类固醇受体超家族成员。
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