Product Name	Anti-Estrogen Sulfotransferase/Cy5.5
Chinese Name	Cy5.5标记的雌激素硫酸转移酶抗体
Alias	Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN.
Research Area	immunology  Growth factors and hormones  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	32kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Subunit: Homodimer. Subcellular Location: Cytoplasm. Tissue Specificity: Liver, intestine and at lower level in the kidney. Similarity: Belongs to the sulfotransferase 1 family. Database links: Entrez Gene: 6783 Human Entrez Gene: 25355 Rat Omim: 600043 Human SwissProt: P49888 Human SwissProt: P52844 Rat Unigene: 479898 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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