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Product Name Anti-Uridine Phosphorylase 1/Cy3 Chinese Name Cy3标记的尿嘧啶核苷磷酸化酶1抗体 Alias UPase 1; UPP1; UPP 1; UPP-1; UrdPase 1; UPP1_HUMAN. Research Area Tumour Cell biology Signal transduction TumourCell biologyMaker Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 34 kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human UPP1/Uridine Phosphorylase 1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA
Function:
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Subunit:
Homodimer.
Similarity:
Belongs to the PNP/UDP phosphorylase family.
Database links:Entrez Gene: 7378 Human
Entrez Gene: 22271 Mouse
Omim: 191730 Human
SwissProt: Q16831 Human
SwissProt: P52624 Mouse
Unigene: 488240 Human
Unigene: 4610 Mouse
Unigene: 101932 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Ka*** | 2 | 2024-08-31 |
Is*** | 2 | 2024-07-08 |
Pe*** | 2 | 2024-02-15 |
Ab*** | 1 | 2023-11-15 |
Ja*** | 2 | 2023-11-03 |
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