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Rabbit Anti-Uridine Phosphorylase 1/Cy3 Conjugated antibody
Rabbit Anti-Uridine Phosphorylase 1/Cy3 Conjugated antibody
UPase 1; UPP1; UPP 1; UPP-1; UrdPase 1; UPP1_HUMAN.
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  • NO.:SL6288R-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-Uridine Phosphorylase 1/Cy3
Chinese Name Cy3标记的尿嘧啶核苷磷酸化酶1抗体
Alias UPase 1; UPP1; UPP 1; UPP-1; UrdPase 1; UPP1_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  TumourCell biologyMaker  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34 kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human UPP1/Uridine Phosphorylase 1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA

Function:
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Subunit:
Homodimer.

Similarity:
Belongs to the PNP/UDP phosphorylase family.

Database links:

Entrez Gene: 7378 Human

Entrez Gene: 22271 Mouse

Entrez Gene: 289801 Rat

Omim: 191730 Human

SwissProt: Q16831 Human

SwissProt: P52624 Mouse

Unigene: 488240 Human

Unigene: 4610 Mouse

Unigene: 101932 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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