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Rabbit Anti-SVH/Cy3 Conjugated antibody
Rabbit Anti-SVH/Cy3 Conjugated antibody
Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; ARM10_HUMAN.
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  • NO.:SL6737R-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-SVH/Cy3
Chinese Name Cy3标记的肝癌蛋白剪接变异体蛋白抗体
Alias Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; ARM10_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  Cyclin  Cell type markers  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 38kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SVH/ARMC10
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.

Function:
May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.

Subunit:
Interacts with the DNA-binding domain of p53/TP53.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain.

Similarity:
Contains 1 ARM repeat.

Database links:

Entrez Gene: 83787 Human

Entrez Gene: 67211 Mouse

Entrez Gene: 296758 Rat

Omim: 611864 Human

SwissProt: Q8N2F6 Human

SwissProt: Q9D0L7 Mouse

SwissProt: B1WBW4 Rat

Unigene: 287412 Human

Unigene: 260782 Mouse

Unigene: 2408 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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