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Rabbit Anti-S100 alpha 2/Cy3 Conjugated antibody
Rabbit Anti-S100 alpha 2/Cy3 Conjugated antibody
S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.
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  • NO.:SL7873R-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Goat,Cat,,lizard)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-S100 alpha 2/Cy3
Chinese Name Cy3标记的S100A2抗体
Alias S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  Cyclin  Binding protein  Cell differentiation  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ,lizard)
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 11kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human S100 alpha 2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.

Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.

Subunit:
Homodimer. Interacts with FKBP4.

Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.

Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.

Database links:
UniProtKB/Swiss-Prot: P29034.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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