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Product Name | Anti-CESK1/Cy3 |
Chinese Name | Cy3标记的分子伴侣CESK1蛋白抗体 |
Alias | CCT8L2; KCNMB3L; T complex protein 1; CESK1; chaperonin containing TCP1, subunit 8 (theta)-like 2; Putative T-complex protein 1 subunit theta-like 2; T complex protein 1; chaperonin containing TCP1, subunit 8 theta-like 2; TCPQM_HUMAN. |
Research Area | Cell biology immunology |
Immunogen Species | Rabbit |
Clonality | Polyclonal |
React Species | (predicted: Human, ) |
Applications | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
Molecular weight | 59kDa |
Form | Lyophilized or Liquid |
Concentration | 1mg/ml |
immunogen | KLH conjugated synthetic peptide derived from human CESK1 (509-557aa) |
Lsotype | IgG |
Purification | affinity purified by Protein A |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Product Detail |
background: CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias. Function: Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis Subcellular Location: Cytoplasm. Similarity: Belongs to the TCP-1 chaperonin family. Database links: Entrez Gene: 150160 Human SwissProt: Q96SF2 Human Unigene: 128342 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Product Name Anti-CESK1/Cy3 Chinese Name Cy3标记的分子伴侣CESK1蛋白抗体 Alias CCT8L2; KCNMB3L; T complex protein 1; CESK1; chaperonin containing TCP1, subunit 8 (theta)-like 2; Putative T-complex protein 1 subunit theta-like 2; T complex protein 1; chaperonin containing TCP1, subunit 8 theta-like 2; TCPQM_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 59kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CESK1 (509-557aa) Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.
Function:
Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the TCP-1 chaperonin family.
Database links:Entrez Gene: 150160 Human
SwissProt: Q96SF2 Human
Unigene: 128342 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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