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Rabbit Anti-KLHL31/Cy3 Conjugated antibody
Rabbit Anti-KLHL31/Cy3 Conjugated antibody
KLHL; BKLHD6; BTB and kelch domain containing protein 6; KBTBD1; Kelch like protein 31; Kelch like protein KLHL; Kelch repeat and BTB domain containing protein 1; KLH31_HUMAN.
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  • NO.:SL8057R-Cy3
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,Zebrafish,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-KLHL31/Cy3
Chinese Name Cy3标记的Kelch样蛋白31抗体
Alias KLHL; BKLHD6; BTB and kelch domain containing protein 6; KBTBD1; Kelch like protein 31; Kelch like protein KLHL; Kelch repeat and BTB domain containing protein 1; KLH31_HUMAN.  
Research Area Tumour  Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Zebrafish, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 70kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human KLHL31
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).

Tissue Specificity:
Strongly expressed in skeletal muscle and weakly in heart. According to PubMed:15302408, not expressed in other tissues. According to PubMed:18719355, abundantly expressed in both embryonic skeletal and heart tissues.

Post-translational modifications:
N-terminus is methylated by METTL11A/NTM1 (By similarity).

Similarity:
Contains 1 BACK (BTB/Kelch associated) domain.
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats.

Database links:
UniProtKB/Swiss-Prot: Q9H511.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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