Product Name	Anti-PNPLA3/Biotin
Chinese Name	生物素标记的脂肪营养素PNPLA3抗体
Alias	Acylglycerol O acyltransferase; Adiponutrin; ADPN; C22orf20; Calcium independent phospholipase A2 epsilon; DJ796I17.1; iPLA(2)epsilon; IPLA2-epsilon; Patatin like phospholipase domain containing 3; patatin like phospholipase domain containing protein 3; phospholipase A2, calcium independent, epsilon.
Research Area	Tumour  Cardiovascular  Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,
Applications	WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	53kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse PNPLA3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008] Function: Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. Subcellular Location: Membrane; Single pass type II membrane protein. DISEASE: Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease description:A condition characterized by accumulation of triglycerides in the liver. It is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries. Similarity: Contains 1 patatin domain. Database links: Entrez Gene: 609368 Dog Entrez Gene: 101131854 Gorilla Entrez Gene: 101824852 Hamster Entrez Gene: 80339 Human Entrez Gene: 100406659 Marmoset (common) Entrez Gene: 116939 Mouse Entrez Gene: 100344884 Rabbit Entrez Gene: 362972 Rat Omim: 609567 Human SwissProt: Q9NST1 Human SwissProt: Q91WW7 Mouse Unigene: 654800 Human Unigene: 390817 Mouse Unigene: 97779 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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