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Product Name Anti-Netrin-G1/Biotin Chinese Name 生物素标记的轴突生长诱向因子G1/神经突起生长导向因子G1抗体 Alias Axon guidance molecule; KIAA0976; Laminet 1; LMNT1; Netrin G1f; Netrin-G1; Ntng1; NTNG1_HUMAN; YLSR571. Research Area Neurobiology Signal transduction Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 54kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Netrin-G1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015].
Function:
Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
Subunit:
Interacts with NGL1.
Subcellular Location:
Cell membrane. Lipid-anchor, GPI-anchor, Extracellular side.
Tissue Specificity:
Highly expressed in the thalamus, with very low expression, if any, in other tissues.
Post-translational modifications:
N-glycosylated.
Similarity:
Contains 3 laminin EGF-like domains.
Contains 1 laminin N-terminal domain.
Database links:
Entrez Gene: 100714441 Guinea pig
Entrez Gene: 100060362 Horse
Entrez Gene: 22854 Human
Entrez Gene: 80883 Mouse
Entrez Gene: 100341879 Rabbit
Omim: 608818 Human
SwissProt: Q9Y2I2 Human
SwissProt: Q8R4G0 Mouse
Unigene: 657434 Human
Unigene: 732535 Human
Unigene: 39262 Mouse
Unigene: 162628 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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