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Product Name Anti-SURF4/Biotin Chinese Name 生物素标记的过量位点蛋白4抗体 Alias 1464:; AL033373; ERV 29; ERV29; FLJ22993; MGC102753; MGC165910; MGC65806; MGC76061; SURF 4; SURF4; SURF4_HUMAN; Surface 4 integral membrane protein; Surfeit 4; Surfeit locus protein 4; Surfeit4; zgc:65806; zgc:77007. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 30kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SURF4 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Function:
May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi.
Subunit:
Found in a complex composed at least of SURF4, TMED2 and TMED10. May interact with LMAN1.
Subcellular Location:
Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Cycles between the endoplasmic reticulum and the Golgi.
Similarity:
Belongs to the SURF4 family.
Database links:Entrez Gene: 6836 Human
Entrez Gene: 20932 Mouse
Omim: 185660 Human
SwissProt: O15260 Human
SwissProt: Q64310 Mouse
Unigene: 512465 Human
Unigene: 300594 Mouse
Unigene: 107863 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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