TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-PNRC2/Biotin Chinese Name 生物素标记的富含脯氨酸核受体共激活因子2抗体 Alias 0610011E17Rik; D4Bwg0593e; FLJ20312; MGC11707; MGC93828; MGC99541; OTTMUSP00000010360; OTTMUSP00000010366; pnrc2; PNRC2_HUMAN; Proline rich nuclear receptor coactivator 2; Proline-rich nuclear receptor coactivator 2; RP11-4M23.5; RP23-161N17.3. Research Area Cell biology Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, ) Applications ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 16kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PNRC2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.
Subcellular Location:
Nucleus. Cytoplasm > P-body.
Tissue Specificity:
Expressed in heart, lung, muscle and brain.
Similarity:
Belongs to the PNRC family. PNRC2 subfamily.
Database links:Entrez Gene: 100505603 Human
Entrez Gene: 55629 Human
Entrez Gene: 52830 Mouse
Omim: 611882 Human
SwissProt: Q9NPJ4 Human
SwissProt: Q9CR73 Mouse
Unigene: 512636 Human
Unigene: 644217 Human
Unigene: 716935 Human
Unigene: 7862 Human
Unigene: 29159 Mouse
Unigene: 118788 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode