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Product Name Anti-SNPH/Biotin Chinese Name 生物素标记的伸展蛋白SNPH抗体 Alias bA314N13.5; KIAA0374; Snph; SNPH_HUMAN; Syntaphilin. Research Area Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 53kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SNPH Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. [provided by RefSeq, Jul 2008]
Function:
Inhibits SNARE complex formation by absorbing free syntaxin-1.
Subcellular Location:
Membrane. Cell junction, synapse, synaptosome.
Tissue Specificity:
Brain specific. Found in synapses.
Database links:Entrez Gene: 9751 Human
Entrez Gene: 241727 Mouse
Omim: 604942 Human
SwissProt: O15079 Human
SwissProt: Q80U23 Mouse
Unigene: 323833 Human
Unigene: 39312 Mouse
Unigene: 133817 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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