Product Name	Anti-RECQ1/Biotin
Chinese Name	生物素标记的DNA解旋酶Q1样抗体
Alias	ATP dependent DNA helicase Q1; DNA helicase Q1 like; DNA helicase RecQ like type 1; RECQ L1; RecQ protein like 1; RecQ protein like; RECQL; RECQL1.
Research Area	Tumour  Neurobiology  Binding protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	72kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RECQ1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008] Function: DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Subunit: Interacts with EXO1 and MLH1. Subcellular Location: Nuclear Tissue Specificity: High expression in heart, lung, skeletal muscle and kidney, low expression in brain. Similarity: Belongs to the helicase family. RecQ subfamily Contains 1 helicase ATP-binding domain Contains 1 helicase C-terminal domain. Database links: Entrez Gene: 5965 Human Entrez Gene: 19691 Mouse Omim: 600537 Human SwissProt: P46063 Human SwissProt: Q9Z129 Mouse Unigene: 235069 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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