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Rabbit Anti-IFT172/Biotin Conjugated antibody
Rabbit Anti-IFT172/Biotin Conjugated antibody
IF172_HUMAN; ift172; Intraflagellar transport 172 homolog (Chlamydomonas); Intraflagellar transport protein 172 homolog; Osm 1; Selective LIM binding factor homolog; SLB; Wim; Wimple homolog.
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Details

Product Name Anti-IFT172/Biotin
Chinese Name 生物素标记的细胞纤毛内转运同源蛋白172抗体
Alias IF172_HUMAN; ift172; Intraflagellar transport 172 homolog (Chlamydomonas); Intraflagellar transport protein 172 homolog; Osm 1; Selective LIM binding factor homolog; SLB; Wim; Wimple homolog.   
Research Area Cell biology  immunology  Transporter  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 198kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human IFT172
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]

Function:
Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.

Subunit:
Interacts with IFT88.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IFT172 family.
Contains 14 TPR repeats.
Contains 9 WD repeats.

Database links:

Entrez Gene: 26160 Human

Omim: 607386 Human

SwissProt: Q9UG01 Human

Unigene: 127401 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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