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Product Name Anti-MCTP2/Biotin Chinese Name 生物素标记的MCTP2蛋白抗体 Alias FLJ11175; FLJ33303; MGC111402; Multiple C2 and transmembrane domain containing protein 2; Multiple C2 domains, transmembrane 2; Multiple C2-domains with two transmembrane regions 2. Research Area Cell biology Signal transduction Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 100kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MCTP2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
MCTP2 is an 878 amino acid multi-pass membrane protein that belongs to the MCTP family. Existing as five alternatively spliced isoforms, MCTP1 binds calcium via its C2 domains in the absence of phospholipids, and is encoded by a gene that maps to human chromosome 15q26.2. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Function:
MCTP2 contains C2 domains which bind calcium in the absence of phospholipids. There are 5 isoforms produced by alternative splicing.
Subcellular Location:
Cell Membrane; multipass membrane protein
Similarity:
Belongs to the MCTP family.
Contains 3 C2 domains.
Database links:Entrez Gene: 55784 Human
Entrez Gene: 244049 Mouse
SwissProt: Q6DN12 Human
SwissProt: Q5RJH2 Mouse
Unigene: 592017 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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