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Rabbit Anti-LYPD1/Biotin Conjugated antibody
Rabbit Anti-LYPD1/Biotin Conjugated antibody
FLJ41033; LY6/PLAUR domain containing 1; Ly6/PLAUR domain-containing protein 1; Lypd1; LYPD1_HUMAN; LYPDC1; MGC29643; PHTS; Putative HeLa tumor suppressor.
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  • NO.:SL18570R-Bio
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-LYPD1/Biotin
Chinese Name 生物素标记的LYPD1蛋白抗体
Alias FLJ41033; LY6/PLAUR domain containing 1; Ly6/PLAUR domain-containing protein 1; Lypd1; LYPD1_HUMAN; LYPDC1; MGC29643; PHTS; Putative HeLa tumor suppressor.  
Research Area Cell biology  Apoptosis  Epigenetics  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Rabbit, )
Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 13kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LYPD1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Product Detail background:
LYPD1 is a 141 amino acid protein that contains one UPAR/Ly6 domain. LYPD1 is a cell membrane protein expressed as three isoforms and encoded by a gene mapping to human chromosome 2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Subcellular Location:
Cell membrane.

Similarity:
Contains 1 UPAR/Ly6 domain.

Database links:

Entrez Gene: 116372 Human

Entrez Gene: 72585 Mouse

Entrez Gene: 360838 Rat

Omim: 610450 Human

SwissProt: Q8N2G4 Human

SwissProt: Q8BLC3 Mouse

SwissProt: Q66H42 Rat

Unigene: 432395 Human

Unigene: 741324 Human

Unigene: 490405 Mouse

Unigene: 231867 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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