Product Name	Anti-SHMT1/Biotin
Chinese Name	生物素标记的丝氨酸甲基化酶cSHMT抗体
Alias	CSHMT; Cytoplasmic serine hydroxymethyltransferase; cytosolic; GLYC_HUMAN; Glycine hydroxymethyltransferase; Serine hydroxymethyltransferase 1 (soluble); Serine hydroxymethyltransferase; Serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMT; Shmt1.
Research Area	Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Rabbit, )
Applications	WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	53kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SHMT1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Interconversion of serine and glycine. Subcellular Location: Cytoplasm. Similarity: Belongs to the SHMT family. Database links: Entrez Gene: 6470 Human Entrez Gene: 20425 Mouse Omim: 182144 Human SwissProt: P34896 Human SwissProt: P50431 Mouse Unigene: 513987 Human Unigene: 636044 Human Unigene: 364956 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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