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Rabbit Anti-TOMM22/Biotin Conjugated antibody
Rabbit Anti-TOMM22/Biotin Conjugated antibody
1C9 2; hTom 22; hTom22; Mitochondrial import receptor subunit TOM 22 homolog; Mitochondrial import receptor subunit TOM22 homolog; Mitochondrial import receptor Tom 22; Mitochondrial import receptor Tom22; MST 065; MST065; MSTP 065; MSTP065; TOM 22; TOM22
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  • NO.:SL17225R-Bio
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name Anti-TOMM22/Biotin
Chinese Name 生物素标记的TOMM22蛋白抗体
Alias 1C9 2; hTom 22; hTom22; Mitochondrial import receptor subunit TOM 22 homolog; Mitochondrial import receptor subunit TOM22 homolog; Mitochondrial import receptor Tom 22; Mitochondrial import receptor Tom22; MST 065; MST065; MSTP 065; MSTP065; TOM 22; TOM22_HUMAN; TOM22; TOMM 22; Translocase of outer membrane 22 kDa subunit homolog; Translocase of outer mitochondrial membrane 22 homolog.  
Research Area Cell biology  Signal transduction  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 15kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TOMM22
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]

Function:
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.

Subunit:
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with TOMM40. Interacts with PPP2R2B (By similarity).

Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the Tom22 family.

Database links:

Entrez Gene: 56993 Human

Entrez Gene: 223696 Mouse

Entrez Gene: 300075 Rat

Omim: 607046 Human

SwissProt: Q9CPQ3 Mouse

SwissProt: Q75Q41 Rat

Unigene: 285005 Human

Unigene: 246435 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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