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Rabbit Anti-GPCR GPR87/Biotin Conjugated antibody
Rabbit Anti-GPCR GPR87/Biotin Conjugated antibody
FKSG 78; FKSG78; G protein coupled receptor 87; G protein coupled receptor 95; G-protein coupled receptor 87; G-protein coupled receptor 95; GPCR87; GPR 87; GPR 95; GPR87; GPR87_HUMAN; GPR95; hGPCR87; KPG 002; KPG_002; MGC131898; Orphan GPCR 87; Probable
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  • NO.:SL16267R-Bio
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name Anti-GPCR GPR87/Biotin
Chinese Name 生物素标记的G protein-coupled receptor87抗体
Alias FKSG 78; FKSG78; G protein coupled receptor 87; G protein coupled receptor 95; G-protein coupled receptor 87; G-protein coupled receptor 95; GPCR87; GPR 87; GPR 95; GPR87; GPR87_HUMAN; GPR95; hGPCR87; KPG 002; KPG_002; MGC131898; Orphan GPCR 87; Probable G protein coupled receptor 87,  
Research Area Tumour  Signal transduction  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 41kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GPCR GPR87
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]

Function:
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 53836 Human

Entrez Gene: 84111 Mouse

Omim: 606379 Human

SwissProt: Q9BY21 Human

SwissProt: Q99MT7 Mouse

Unigene: 591292 Human

Unigene: 60267 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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