Product Name	Anti-EXOC7/Biotin
Chinese Name	生物素标记的EXOC7蛋白抗体
Alias	2 5 3p; DKFZp686J04253; EX070; EXO70; Exo70p; EXOC 1; EXOC 7; EXOC1; Exoc7; EXOC7_HUMAN; Exocyst complex component 7; Exocyst complex component Exo70; FLJ40965; FLJ46415; KIAA1067; Rexo70; YJL085W.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, )
Applications	WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	83kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human EXOC7
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011] Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Subcellular Location: Cytoplasm > cytosol. Cell membrane. Translocates, as a preformed complex with SEC6 and SEC8, to the plasma membrane in response to insulin through the activation of ARHQ. Similarity: Belongs to the EXO70 family. Database links: Entrez Gene: 23265 Human Entrez Gene: 417361 Chicken Entrez Gene: 505568 Cow Entrez Gene: 53413 Mouse Entrez Gene: 64632 Rat Entrez Gene: 406723 Zebrafish Omim: 608163 Human SwissProt: Q5ZIN3 Chicken SwissProt: Q3ZC43 Cow SwissProt: Q9UPT5 Human SwissProt: O35250 Mouse SwissProt: O54922 Rat SwissProt: Q7ZTX5 Zebrafish Unigene: 514496 Human Unigene: 533985 Human Unigene: 22530 Mouse Unigene: 45761 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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