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Product Name Anti-CPVL/Biotin Chinese Name 生物素标记的卵黄样羧肽酶抗体 Alias Carboxypeptidase; Carboxypeptidase vitellogenic like; carboxypeptidase WUG; CP-Mac carboxypeptidase; cpvl; CPVL_HUMAN; HVLP; MGC10029; Probable serine carboxypeptidase CPVL; Serine carboxypeptidase vitellogenic like; VCP like protein; VCP-like protein; Vitellogenic carboxypeptidase like protein; Vitellogenic carboxypeptidase-like protein; vitellogenic-like; VLP. Research Area Cell biology Binding protein Ubiquitin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 54kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CPVL Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a carboxypeptidase and bears strong sequence similarity to serine carboxypeptidases. Carboxypeptidases are a large class of proteases that act to cleave a single amino acid from the carboxy termini of proteins or peptides. The exact function of this protein, however, has not been determined. At least two alternatively spliced transcripts which encode the same protein have been observed. [provided by RefSeq, Jul 2008]
Function:
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
Tissue Specificity:
Expressed in macrophages but not in other leukocytes. Abundantly expressed in heart and kidney. Also expressed in spleen, leukocytes, and placenta.
Similarity:
Belongs to the peptidase S10 family.
Database links:Entrez Gene: 54504 Human
Omim: 609780 Human
SwissProt: Q9H3G5 Human
Unigene: 233389 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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