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Product Name Anti-CCL6/Biotin Chinese Name 生物素标记的嗜酸粒细胞趋化蛋白CCL6抗体 Alias C-C motif chemokine 6; C10; CCL 6; Chemokine C C motif Ligand 6; Chemokine C-C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6. Research Area immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Mouse, Rat, ) Applications ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 10kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse CCL6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
CCL6 (C10) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. It is a potent chemoattractant of macrophages, but it can also attract B cells, CD4+ lymphocytes and eosinophils. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be induced under conditions suitable for myeloid cell differentiation. CCL6 (C10) was originally identified as a transcript that is induced in bone marrow cells upon stimulation of GMCSF. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
Function:
CCL6(22-95) and CCL6(23-95) are potent chemoattractants.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.
Similarity:
Belongs to the intercrine beta (chemokine CC) family.
Database links:Entrez Gene: 20305 Mouse
SwissProt: P27784 Mouse
Unigene: 137 Mouse
Unigene: 7857 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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