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Product Name Anti-BCMP101/Biotin Chinese Name 生物素标记的乳腺癌膜相关蛋白101抗体 Alias BCMP101; Breast cancer membrane protein 101; Breast cancer membrane-associated protein 101; FA84B_HUMAN; FAM84B; Family with sequence similarity 84 member B; neurological/sensory 2; NSE2; OTTHUMP00000228215; Protein FAM84B; Protein NSE2; RGD1562236. Research Area Tumour Cell biology immunology Neurobiology TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, ) Applications WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 34kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FAM84B/BCMP101 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Tissue Specificity:
Expressed in esophageal squamous cell carcinomas.
Similarity:
Belongs to the FAM84 family.
Database links:
UniProtKB/Swiss-Prot: Q96KN1.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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